Dr. Barry Sears is a leading authority in the field of dietary control of hormonal response. A former research scientist at the Boston University School of Medicine and the Massachusetts Institute of Technology, Dr. Sears has dedicated his research efforts over the past 25 years to the study of lipids and their inflammatory role in the development of chronic disease. He holds 13 U.S. Patents in the areas of intravenous drug delivery systems and hormonal regulation for the treatment of cardiovascular disease.
The turning point in his research occurred when the 1982 Nobel Prize in Medicine was awarded for discoveries of the role that certain hormones, known as eicosanoids, play in the development of cardiovascular disease, diabetes, autoimmune diseases and cancer. It is the degree of inflammation controlled by eicosanoids that is the linking factor to these various chronic disease conditions. Since eicosanoids are derived from dietary fat, he reasoned that one could apply intravenous drug delivery principles to nutrition in order to control these exceptionally powerful hormonal responses with laser-like precision; in essence by treating food as if it were a drug.
His research has led to various patents in the area of hormonal control by essentially using food as an oral drug delivery system to modulate eicosanoids especially for cardiovascular and diabetic patents.
The widespread understanding of the revolutionary impact of Dr. Sears’ work in dietary control of hormonal response began with the publication of his landmark book, The Zone. Since its publication in June 1995, The Zone, which became a #1 best seller on the New York Times book list. Dr. Sears has also authored a total of ten books on his Zone technology that have sold more than four million copies, and they have been translated into 22 languages in 40 countries.
Dr. Sears’ insight into the hormonal consequences of the diet has been confirmed by numerous published studies, many of them done at Harvard Medical School. As a result of his impact on nutrition and health, Dr. Sears is featured frequently in national media such as 20/20, Today, Good Morning America, CBS Morning News, CNN, MSNBC, and USA Today.
Dr. Sears continues his ongoing research as president of Zone Labs, a biotechnology company in Danvers, MA. In addition to continuing research on the hormonal effects of food, Dr. Sears has expanded his research to developing, innovative dietary approaches to treating neurological conditions and improved cognitive function by re-modeling neural networks in the brain, in addition to his on-going work in treating heart disease and type 2 diabetes. All of this research work is funded through his non-profit research foundation, the Inflammation Research Foundation.